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Topo IIIBeta-1 Polyclonal Antibody, 50ul Micro Centrifuge Tubes The 3-phosphoinositide dependent protein kinase-1

SKU: 54432208355

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SEK185.00 SEK207.00

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Topo IIIBeta-1 Polyclonal Antibody, 50ul Micro Centrifuge Tubes The 3-phosphoinositide dependent protein kinase-1TOP3B encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome

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Description

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

Mutant beta globin causes sickle cell anemia

Plays an important role in tumor suppression through p53/TP53 regulation

Belongs to the EBP2 family

This gene encodes a ribosomal protein that is a component of the 40S subunit

Topo IIIBeta-1 Polyclonal Antibody, 50ul Micro Centrifuge Tubes The 3-phosphoinositide dependent protein kinase-1TOP3B encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome

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