Vangl1 Polyclonal Antibody, 100ul Immunoassays This protein belongs to the

This protein belongs to the Pmr5-Cas1p-esterase subfamily in that it contains the catalytic triad comprised of serine| aspartate and histidine and lacks two conserved regions (glycine after strand S2 and GxND motif)

the protein has 3' to 5' exonuclease activity and endonuclease activity

which is processed to yield both alpha and beta chains

The encoded protein acts as an intermediary factor for the ligand-dependent activity of these nuclear receptors

this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells

Vangl1 Polyclonal Antibody, 100ul Immunoassays This protein belongs to theVANGL1 encodes a member of the tretraspanin family. The vang like protein 1 may be involved in mediating intestinal trefoil factor induced wound healing in the intestinal mucosa. Mutations in this gene are associated with neural tube defects. Alternate splicing results in multiple transcript variants.