SAE1 Polyclonal Antibody, 100ul Metabolic enzymes The encoded protein may suppress

The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways

The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins

This protein resembles yeast Prp16 more closely than other DEAD/H family members

Variations in this gene have been linked to metabolic syndrome

Sumoylation inhibits the AP-1 transcriptional activity and is| itself| inhibited by Ras-activated phosphorylation on Thr-232

SAE1 Polyclonal Antibody, 100ul Metabolic enzymes The encoded protein may suppressPosttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO activating enzyme for the sumoylation of proteins.