BubR1 Polyclonal Antibody, 100ul 3D Culture and proposed to regulate cell-cycle

and proposed to regulate cell-cycle progression during spermatogenesis

The encoded protein is a calcium-binding regulatory protein that interacts with DNA-dependent protein kinase catalytic subunits (DNA-PKcs)

and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14

not all variants have been described

This gene encodes a member of the low density lipoprotein (LDL) receptor family

BubR1 Polyclonal Antibody, 100ul 3D Culture and proposed to regulate cell-cycleBUB1B encodes a kinase involved in spindle checkpoint function. The protein (BUB1 mitotic checkpoint serine threonine kinase B)has been localized to the kinetochore and plays a role in the inhibition of the anaphase promoting complex cyclosome (APC C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.