FKRP Polyclonal Antibody, 100ul 3D Cell Culture Consumables the cellular RAF1 protein can

the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2

also known as action myoclonus-renal failure syndrome (AMRF)

and is essential for the normal development of dorsal limb structures

The inhibitory activity is enhanced by the presence of heparin

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell

FKRP Polyclonal Antibody, 100ul 3D Cell Culture Consumables the cellular RAF1 protein canFKRP (fukutin related protein) encodes a protein which is targeted to the medial Golgi apparatus and is necessary for posttranslational modification of dystroglycan. Mutations in FKRP have been associated with congenital muscular dystrophy, mental retardation, and cerebellar cysts. Several alternatively spliced transcript variants of FKRP have been described, but the full length nature of some of these variants has not been determined.