Dok-3 Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) This gene is testis-specific and

This gene is testis-specific and contains a polymorphic region| resulting in isoforms with varying numbers of C-terminal repeats

A related pseudogene has been identified in the pseudoautosomal region of chromosome Y

PARD family members interact with other PARD family members and other proteins

differing from other members at a number of conserved residues in the activation and nucleotide binding domains

The nuclear RNA export factor 1 of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA

Dok-3 Polyclonal Antibody, 100ul Enzyme-Linked Immunosorbent Assay (ELISA) This gene is testis-specific andDok 1, Dok 2 and Dok 3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok 1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok 2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr Abl. Dok 3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B