dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have also been described for this gene

It may function as an integrator of transcription repression and nuclear receptor signaling

Overexpression of MARK leads to hyperphosphorylation of MAPs

Phosphorylated by ATR upon DNA damage

MSH6 encodes a member of the DNA mismatch repair MutS family

dTMP Kinase Polyclonal Antibody, 50ul Low-speed Centrifuges Alternatively spliced transcript variants encodingThymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5 Fluorouracil (5 FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle