MBD2 Rabbit Polyclonal Antibody, 100ul Cellular Function Assays Oxidative stress is hypothesized to

Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes

Alternative splicing may result in several transcript variants| however

This gene encodes a 28S subunit protein that is similar to the chicken pro-apoptotic protein p52

General transcription factor 3C polypeptide 3 encoded by GTF3C3 is part of the TFIIIC2 complex

so that the gene pair shares a common promoter

MBD2 Rabbit Polyclonal Antibody, 100ul Cellular Function Assays Oxidative stress is hypothesized toDNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2 MBD1 MBD2 MBD3 and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl CpG binding domain (MBD). Each of these proteins with the exception of MBD3 is capable of binding specifically to methylated DNA. MECP2 MBD1 and MBD2 can also repress transcription from methylated gene