Phospho-Akt1 (S129) Polyclonal Antibody, 100ul Variant Libraries Increased expression of this gene

Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer

BH1 and BH2 domains

Transcripts from this gene contain a palindromic termination element

form a heterotetrameric complex called an adaptor

The various TLRs exhibit different patterns of expression

Phospho-Akt1 (S129) Polyclonal Antibody, 100ul Variant Libraries Increased expression of this geneThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a