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CENPN Polyclonal Antibody, 50ul Apoptosis & Autophagy NKTR encodes a membrane-anchored protein

SKU: 55630006923

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SEK185.00 SEK208.00

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CENPN Polyclonal Antibody, 50ul Apoptosis & Autophagy NKTR encodes a membrane-anchored proteinThe protein encoded by this gene forms part of the nucleosome associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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Description

NKTR encodes a membrane-anchored protein with a hydrophobic amino terminal domain and a cyclophilin-like PPIase domain

In addition| the C-terminal kinase domain binds to its own N-terminal region| suggesting potential negative regulation through interference with complex formation via intramolecular binding

Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP

these filters provide superior separation and purification of small molecules

Permeable for monovalent cations sodium

CENPN Polyclonal Antibody, 50ul Apoptosis & Autophagy NKTR encodes a membrane-anchored proteinThe protein encoded by this gene forms part of the nucleosome associated complex and is important for kinetochore assembly. It is bound to kinetochores during S phase and G2 and recruits other proteins to the centromere. Pseudogenes of this gene are located on chromosome 2. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

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