ATF-6Beta Polyclonal Antibody, 50ul miRNA / siRNA Synthesis This gene encodes a member

This gene encodes a member of the thioredoxin superfamily

GO annotations related to this gene include receptor activity and semaphorin receptor binding

In response to cellular metabolic stresses

a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8

Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia

ATF-6Beta Polyclonal Antibody, 50ul miRNA / siRNA Synthesis This gene encodes a memberThe protein (activating transcription factor 6 beta) encoded by ATF6B is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6 alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER