Akt1 Polyclonal Antibody, 20ul[BT-AP00346] RNA Tools Alternative splicing results in multiple

Alternative splicing results in multiple variants encoding distinct isoforms

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AKT2 was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

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as it contains characteristic adjacent cysteine residues

Akt1 Polyclonal Antibody, 20ul[BT-AP00346] RNA Tools Alternative splicing results in multipleThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a