AMPK alpha 1 Polyclonal Antibody, 20ul[BT-AP14206] Enzymes & Activity Assays The neuregulin 1 encoded by

The neuregulin 1 encoded by NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems

but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC

Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2

thereby terminating the signal

where it may be involved in nuclear inositol phosphate signaling processes

AMPK alpha 1 Polyclonal Antibody, 20ul[BT-AP14206] Enzymes & Activity Assays The neuregulin 1 encoded byThe protein encoded by this gene belongs to the ser thr protein kinase family. It is the catalytic subunit of the 5' prime AMP activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that