14-3-3-pan(Acetyl Lys51/49) Polyclonal Antibody, 100ul Subcellular Fractions A long isoform of the

A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors

regulates the kinase activity

Among its related pathways are Cellular response to heat stress and Cellular Senescence

This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis

This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro| thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components

14-3-3-pan(Acetyl Lys51/49) Polyclonal Antibody, 100ul Subcellular Fractions A long isoform of theThis gene encodes a protein belonging to the 14 3 3 family of proteins members of which mediate signal transduction by binding to phosphoserine containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants which encode the