Rat Transcription Factor A, Mitochondrial, TFAM ELISA Kit, 96T Protein Post-translational Modification The encoded protein is characterized

The encoded protein is characterized by a cysteine-rich with epidermal growth factor-like domain

This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding

GO annotations related to this gene include calcium ion binding and phosphoric diester hydrolase activity

Luciferase from the firefly has become one of the more widely used reporter proteins for the study of gene expression

Mutations in this gene cause nemaline myopathy type 3

Rat Transcription Factor A, Mitochondrial, TFAM ELISA Kit, 96T Protein Post-translational Modification The encoded protein is characterized[Isoform Mitochondrial]: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Component of the mitochondrial transcription initiation complex, composed at least of TFB2M, TFAM and POLRMT that is required for basal transcription of mitochondrial DNA. In this complex, TFAM recruits POLRMT to a specific promoter whereas TFB2M induces structural changes in POLRMT to enable promoter opening and trapping