UBR5 Polyclonal Antibody, 100ul Recombinant Ab Production a key enzyme involved in

a key enzyme involved in tumor invasion and metastasis

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integrin signaling and cell adhesion

This protein is a selenoprotein

Also highly expressed in ovarian and leukemia cell lines

UBR5 Polyclonal Antibody, 100ul Recombinant Ab Production a key enzyme involved inUBR5 encodes a progestin induced protein, which belongs to the HECT (homology to E6 AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin protein ligases, targeting specific proteins for ubiquitin mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.