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GCP4 Polyclonal Antibody, 50ul Organelle Studies The protein encoded by HNRNPDL

SKU: 56259921201

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GCP4 Polyclonal Antibody, 50ul Organelle Studies The protein encoded by HNRNPDLTUBGCP4 encodes a component of the gamma tubulin ring complex, gamma tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C terminal domain is essential and sufficient for

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Description

The protein encoded by HNRNPDL has two RRM domains that bind to RNAs

encoded by the CLIC4 gene

Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP

The protein is an important drug target for the treatment of type 2 diabetes and stroke

Increased enzymatic activity causes hyperfibrinolysis

GCP4 Polyclonal Antibody, 50ul Organelle Studies The protein encoded by HNRNPDLTUBGCP4 encodes a component of the gamma tubulin ring complex, gamma tubulin complex component 4, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C terminal domain is essential and sufficient for

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