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RPA32(Phospho Thr21) Polyclonal Antibody, 20ul Purification The encoded protein can act

SKU: 56303229856

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RPA32(Phospho Thr21) Polyclonal Antibody, 20ul Purification The encoded protein can actRequired for DNA recombination, repair and replication. The activity of RP A is mediated by single stranded DNA binding and protein interactions.,PTM: Phosphorylated in a cell cycle dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC DNA PK in the presence of Ku and DNA, and by CDC2.,subcellular location: Also present in PML

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Description

The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes

q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2| and a t(8

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Elevated expression of matrix metallopeptidase 17 protein has been observed in osteoarthritis and multiple human cancers

The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and| a C-terminal HECT ubiquitin ligase catalytic domain

RPA32(Phospho Thr21) Polyclonal Antibody, 20ul Purification The encoded protein can actRequired for DNA recombination, repair and replication. The activity of RP A is mediated by single stranded DNA binding and protein interactions.,PTM: Phosphorylated in a cell cycle dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC DNA PK in the presence of Ku and DNA, and by CDC2.,subcellular location: Also present in PML

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