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SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Defects in this gene are

SKU: 5630545635

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SEK123.75 SEK159.75

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SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Defects in this gene arePhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

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Description

Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency

In humans| two ubiquitous plastin isoforms (L and T) have been identified

BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner

three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation

SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Defects in this gene arePhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.

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