UB2L3 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The protein encoded by MRC1

The protein encoded by MRC1 is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages

Translocated to the nucleus on Ser-151 dephosphorylation

Among its related pathways are Development Slit-Robo signaling and Cytoskeleton remodeling Neurofilaments

a disorder that is characterized by hypercalcemia and skeletal defects

interacts with major histocompatibility complex class I ligands

UB2L3 Polyclonal Antibody, 50ul Human Genome Knockout Libraries The protein encoded by MRC1The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes (E1s), ubiquitin conjugating enzymes (E2s) and ubiquitin protein ligases (E3s). This gene encodes a member of the E2 ubiquitin conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of