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NRAM2 Rabbit Polyclonal Antibody, 50ul Fluorescent Staining Glutamic-oxaloacetic transaminase is a pyridoxal

SKU: 5650321104

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NRAM2 Rabbit Polyclonal Antibody, 50ul Fluorescent Staining Glutamic-oxaloacetic transaminase is a pyridoxalThis gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms

Does not associate with the C1 complex

The protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease| Yme1p

The encoded protein lacks the protein destabilizing (PEST) sequence that is present in other family members

in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants

NRAM2 Rabbit Polyclonal Antibody, 50ul Fluorescent Staining Glutamic-oxaloacetic transaminase is a pyridoxalThis gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.

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