DEN1A Rabbit Polyclonal Antibody, 50ul Fluorescent Staining It is reported to play

It is reported to play a role in the internalization of IL13

This gene results in three transcript variants encoding distinct isoforms

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eosinophils and natural killer cells

May be involved in regulation of gene expression at the post-transcriptional level or in ribosome biogenesis in cancer cells

DEN1A Rabbit Polyclonal Antibody, 50ul Fluorescent Staining It is reported to playClathrin (see MIM 118955) mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family such as DENND1A function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein 2 (AP2; see MIM 601024). Thus connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson 2010