Apaf-1-ALT Polyclonal Antibody, 20ul Molecular Sciences 1-10μl Natural Color Pipet Micro

1-10μl Natural Color Pipet Micro Tips

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Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process

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Apaf-1-ALT Polyclonal Antibody, 20ul Molecular Sciences 1-10μl Natural Color Pipet MicroAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD 40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent