SOCS-1 Polyclonal Antibody, 100ul Culture Media The angiopoietin 1 encoded by

The angiopoietin 1 encoded by ANGPT1 is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation

The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF

The centromeric copy may be a modifier of disease caused by mutation in the telomeric copy

resulting in amino acid changes at three positions in the N-terminus of the protein

It interacts with tumor suppressor p53 and p300

SOCS-1 Polyclonal Antibody, 100ul Culture Media The angiopoietin 1 encoded bySOCS1 encodes a member of the STAT induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2 GM CSF, and interferon (IFN) gamma. Suppressor of cytokine signaling 1 encoded by this gene functions downstream of cytokine