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TOP1M Polyclonal Antibody, 50ul Endonucleases & Exonucleases Fibrinogen-like protein 1 is homologous

SKU: 56902138264

4.1
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TOP1M Polyclonal Antibody, 50ul Endonucleases & Exonucleases Fibrinogen-like protein 1 is homologousThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

Fibrinogen-like protein 1 is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs)

but the full-length nature of some of these variants has not been defined

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Gaucher disease and Usher syndrome

TOP1M Polyclonal Antibody, 50ul Endonucleases & Exonucleases Fibrinogen-like protein 1 is homologousThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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