Rat Heparanase, HPA ELISA Kit, 96T Cell Culture Plates Contains 1 PUA domain

Contains 1 PUA domain

The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation

Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation

Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle (PubMed: 10021340)

but not that on GnRH-stimulated secretion of LH (By similarity)

Rat Heparanase, HPA ELISA Kit, 96T Cell Culture Plates Contains 1 PUA domainEndoglycosidase that cleaves heparan sulfate proteoglycans (HSPGs) into heparan sulfate side chains and core proteoglycans. Participates in extracellular matrix (ECM) degradation and remodeling. Selectively cleaves the linkage between a glucuronic acid unit and an N sulfo glucosamine unit carrying either a 3 O sulfo or a 6 O sulfo group. Can also cleave the linkage between a glucuronic acid unit and an N sulfo glucosamine unit carrying a 2 O sulfo