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MerTK Polyclonal Antibody, 100ul Centrifugal Filter This gene was originally thought

SKU: 57409484572

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MerTK Polyclonal Antibody, 100ul Centrifugal Filter This gene was originally thoughtMERTK is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine protein kinase mer, with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

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Description

This gene was originally thought to be one of the two pseudogenes (CGB1 and CGB2) of CGB subunit

breast and other female reproductive tissues

CGREF1 (Cell Growth Regulator With EF-Hand Domain 1) is a Protein Coding gene

but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase

IRAK3 encodes a member of the interleukin-1 receptor-associated kinase protein family

MerTK Polyclonal Antibody, 100ul Centrifugal Filter This gene was originally thoughtMERTK is a member of the MER AXL TYRO3 receptor kinase family and encodes a transmembrane protein, tyrosine protein kinase mer, with two fibronectin type III domains, two Ig like C2 type (immunoglobulin like) domains, and one tyrosine kinase domain. Mutations in MERTK have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

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