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APS Polyclonal Antibody, 50ul Cell Culture Mutations in this gene impair

SKU: 57461992970

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PLN162.00 PLN188.00

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APS Polyclonal Antibody, 50ul Cell Culture Mutations in this gene impairThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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Description

Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections

Mutations in this gene result in cherubism

The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity

This protein may be involved in the onset of pain associated with peripheral neuropathy

VitroINK® Bioink Starter Kit contains both bioink and the complete mixing kit to prepare the cell bioink mixture for 3D bioprinting

APS Polyclonal Antibody, 50ul Cell Culture Mutations in this gene impairThe SH2B adaptor protein 2 encoded by SH2B2 is expressed in B lymphocytes and contains pleckstrin homology and src homology 2 (SH2) domains. In Burkitt's lymphoma cell lines, it is tyrosine phosphorylated in response to B cell receptor stimulation. Because it binds Shc independent of stimulation and Grb2 after stimulation, it appears to play a role in signal transduction from the receptor to the Shc Grb2 pathway.

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