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PAK gamma(Phospho Ser20) Polyclonal Antibody, 50ul Cell Screening and Imaging especially after a traumatic brain

SKU: 57542847900

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PAK gamma(Phospho Ser20) Polyclonal Antibody, 50ul Cell Screening and Imaging especially after a traumatic brainThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role

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Description

especially after a traumatic brain injury

Pseudogenes of this gene are found on chromosomes 13 and 17

The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene

The product of this gene may play a role in the regulation of cartilage differentiation

Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin

PAK gamma(Phospho Ser20) Polyclonal Antibody, 50ul Cell Screening and Imaging especially after a traumatic brainThe p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase mediated apoptosis, and may play a role

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