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DCTN4 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos associated with TRF1

SKU: 57543469191

4.2
USD97.20 USD139.20

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DCTN4 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos associated with TRF1Could have a dual role in dynein targeting and in ACTR1A Arp1 subunit of dynactin pointed end capping. Could be involved in ACTR1A pointed end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.,Belongs to the dynactin subunit 4 family.,subcellular location: Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization

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Description

associated with TRF1

and cancer growth and metastasis

Alternative promoter and translation initiation site usage allows this gene to exert spatial and temporal specificity to cAMP responsiveness

but it may play a role in vesicle function and nervous system development

One or two of these subunits| together with the well-conserved catalytic subunit| can form the PP1 holoenzyme| where the regulatory subunit functions to regulate substrate specificity and/or targeting to a particular cellular compartment

DCTN4 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos associated with TRF1Could have a dual role in dynein targeting and in ACTR1A Arp1 subunit of dynactin pointed end capping. Could be involved in ACTR1A pointed end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.,Belongs to the dynactin subunit 4 family.,subcellular location: Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin. Overexpression does not disrupt microtubule organization

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