LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis see MIM 164011) through BCL10

see MIM 164011) through BCL10 (MIM 603517) (Wang et al

this protein moves to the nucleus and stimulates transcription of target genes

They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit

Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm

Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation

LRP1 Polyclonal Antibody, 20ul Site-directed Mutagenesis see MIM 164011) through BCL10LRP1 encodes a member of the low density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2 macroglobulin