N2DL3 Polyclonal Antibody, 100ul Gene Synthesis An important paralog of this

An important paralog of this gene is NAA16

SIAH2 encodes E3 ubiquitin-protein ligase SIAH2 that is a member of the seven in absentia homolog (SIAH) family

is expressed in a variety of tissues with the highest levels in heart and pancreas

as a sensor for oxidative stress

The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family

N2DL3 Polyclonal Antibody, 100ul Gene Synthesis An important paralog of thisThe protein encoded by this gene is one of several related ligands of the KLRK1 NKG2D receptor, which is found in primary NK cells. Binding of these ligands to the receptor activates several signal transduction pathways, including the JAK2, STAT5, and ERK pathways. The encoded protein is expressed solubly and on the surface of many tumor cells, making it potentially an important target for therapeutics.