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SOD2 Polyclonal Antibody, 50ul[BT-AP14364] NGS Oligos It contains in its 5'

SKU: 57621140308

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SOD2 Polyclonal Antibody, 50ul[BT-AP14364] NGS Oligos It contains in its 5'This gene is a member of the iron manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

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Description

It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic

point mutations

it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones

Our adenoviral packaging system can accommodate large gene fragments and ensures high-level expression of target genes

however| not all variants have been fully characterized

SOD2 Polyclonal Antibody, 50ul[BT-AP14364] NGS Oligos It contains in its 5'This gene is a member of the iron manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.

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