MKP-3 Polyclonal Antibody, 50ul Glassware It may also play a

It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation

1-10μl volumes

Alternative splicing results in four transcript variants encoding four distinct isoforms

Exon 1 encodes the leader peptide| exons 2 and 3 encode the two extracellular domains| exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail

transcriptional interference

MKP-3 Polyclonal Antibody, 50ul Glassware It may also play aThe dual specificity phosphatase 6 encoded by DUSP6 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine threonine and phosphotyrosine residues. They negatively regulate members of the mitogen activated protein (MAP) kinase superfamily (MAPK ERK, SAPK JNK, p38), which are associated with cellular proliferation and differentiation. Different