BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos with biallelic

with biallelic

an bind to the surface of B-lymphoma cells

a transmembrane segment

Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35

Alternate splicing of this gene generates several transcript variants encoding different isoforms

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos with biallelicBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal