Zic1/2/3/4/5 Polyclonal Antibody, 100ul Electrophoresis & Labeling beginning with the sequence PFXYD

beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids

a polyfunctional cytokine that is involved in cellular differentiation

Isoform 2 is testis specific

but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal

is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense

Zic1/2/3/4/5 Polyclonal Antibody, 100ul Electrophoresis & Labeling beginning with the sequence PFXYDZIC1 (Zic family member 1) encodes a member of the ZIC family of C2H2 type zinc finger proteins. Members of this family are important during development. Aberrant expression of ZIC1 is seen in medulloblastoma, a childhood brain tumor. ZIC1 is closely linked to the gene encoding zinc finger protein of the cerebellum 4, a related family member on chromosome 3. ZIC1 encodes a transcription factor that can bind and transactivate the apolipoprotein E gene.