PEA-15 Polyclonal Antibody, 20ul[BT-AP07044] Hybridoma Antibody Sequencing Activation of this receptor leads

Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases

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PKMYT1 encodes a member of the serine/threonine protein kinase family

MIM 608507) and DRP1 (DNM1L

Functions also as a receptor for aldosterone mediating rapid regulation of vascular contractibility through the PI3K/ERK signaling pathway

PEA-15 Polyclonal Antibody, 20ul[BT-AP07044] Hybridoma Antibody Sequencing Activation of this receptor leadsPEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.