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Cytokeratin 8(Phospho Ser432) Polyclonal Antibody, 20ul Immuno Plates In mouse an alternatively spliced

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Cytokeratin 8(Phospho Ser432) Polyclonal Antibody, 20ul Immuno Plates In mouse an alternatively splicedThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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Description

In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts

Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system

and Axenfeld-Rieger anomaly

This gene encodes an unconventional myosin

It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes

Cytokeratin 8(Phospho Ser432) Polyclonal Antibody, 20ul Immuno Plates In mouse an alternatively splicedThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal

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