EMR2 (Cleaved-Leu517) Rabbit Polyclonal Antibody, 50ul DNA Fragments The GDP-dissociation inhibitors (GDIs) play

The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP

May be involved in melanosomal transport and docking

This gene was initially mapped to chromosome 14

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit

EMR2 (Cleaved-Leu517) Rabbit Polyclonal Antibody, 50ul DNA Fragments The GDP-dissociation inhibitors (GDIs) playThis gene encodes a member of the class B seven span transmembrane (TM7) subfamily of G protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor like domains coupled to a TM7 domain via a mucin like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell cell adhesion through interaction with chondroitin sulfate