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Ref-1 (Acetyl Lys7) Polyclonal Antibody, 50ul Serum which is composed of 13

SKU: 58086684678

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Ref-1 (Acetyl Lys7) Polyclonal Antibody, 50ul Serum which is composed of 13Apurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

which is composed of 13 subunits: EIF3A

An important paralog of this gene is GPR61

The beta subunit may assist in binding of the phospholipid substrate (Probable)

The protein encoded by this gene belongs to the PI3/PI4-kinase family

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells

Ref-1 (Acetyl Lys7) Polyclonal Antibody, 50ul Serum which is composed of 13Apurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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