Phospho-CD40 (T254) Polyclonal Antibody, 100ul Cell Labeling & Imaging This gene location is also

This gene location is also the candidate region of two different neurologic diseases: early-onset parkinsonism (Waisman syndrome) and X-linked mental retardation (MRX3)

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency

PARP1 (poly(ADP-ribose) polymerase 1) encodes a chromatin-associated enzyme

Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens

The protein encoded by this gene is a member of the mini-chromosome maintenance (MCM) protein family that are essential for the initiation of eukaryotic genome replication

Phospho-CD40 (T254) Polyclonal Antibody, 100ul Cell Labeling & Imaging This gene location is alsoCD40 (CD40 molecule) is a member of the TNF receptor superfamily. The encoded protein is a receptor on antigen presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor