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Oct-2 Polyclonal Antibody, 20ul Peptide Modification 53BP1 activates the checkpoint kinase

SKU: 58237470444

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Oct-2 Polyclonal Antibody, 20ul Peptide Modification 53BP1 activates the checkpoint kinasePOU class 2 homeobox 2 encoded by POU2F2 is a homeobox containing transcription factor of the POU domain family. POU class 2 homeobox 2 binds the octamer sequence 5' ATTTGCAT 3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for POU2F2.

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Description

53BP1 activates the checkpoint kinase ATM and promotes DNA double strand break repair via nonhomologous end joining (NHEJ) repair pathway

members of which encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms

BCL-2 family members are known to be regulators of programmed cell death

The sequence data

This protein is reported to interact with

Oct-2 Polyclonal Antibody, 20ul Peptide Modification 53BP1 activates the checkpoint kinasePOU class 2 homeobox 2 encoded by POU2F2 is a homeobox containing transcription factor of the POU domain family. POU class 2 homeobox 2 binds the octamer sequence 5' ATTTGCAT 3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for POU2F2.

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