Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment Reticulons are necessary for proper

Reticulons are necessary for proper generation of tubular endoplasmic reticulum and likely play a role in intracellular vesicular transport

TACC3 encodes a member of the transforming acidic colied-coil protein family

Interacts with RIP and XPA

The genes in this cluster encode members of the cancer/testis (CT) family of antigens| and are distinct from other CT antigens

Appears to function synergistically with RBM14 as a transcriptional coactivator

Stat2 (Acetyl Lys384) Rabbit Polyclonal Antibody, 50ul In vitro Assessment Reticulons are necessary for properSignal transducer and activator of transcription that mediates signaling by type I IFNs (IFN alpha and IFN beta). Following type I IFN binding to cell surface receptors Jak kinases (TYK2 and JAK1) are activated leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize associate with ISGF3G IRF 9 to form a complex termed ISGF3 transcription factor that enters the nucleus. ISGF3 binds to the IFN stimulated response