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This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1|19)

which are involved in pleiotropic effects of signal transduction

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen

This gene encodes a member of the kelch-related family of actin-binding proteins

HSF-27 Polyclonal Antibody, 50ul Plates & Dishes Take your mixing to theCDK5RAP3 encodes CDK5 regulatory subunit associated protein 3 that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms.