IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome Knockout studies in mice suggest

Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system

The encoded protein plays a critical role in cell proliferation

This cytokine has pleiotropic effects in immunoregulation and inflammation

It is associated with CREM and confers a powerful transcriptional activation function

and thus produce an isoform containing a shorter N-terminus

IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome Knockout studies in mice suggestIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.