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FXYD3 Rabbit Polyclonal Antibody, 50ul Deep Well Plates and its 3' end overlaps

SKU: 58474040024

4.1
PLN162.00 PLN187.00

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FXYD3 Rabbit Polyclonal Antibody, 50ul Deep Well Plates and its 3' end overlapsThis gene belongs to a small family of FXYD domain containing regulators of Na+ K+ ATPases which share a 35 amino acid signature sequence domain beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion pumps and ion channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript

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Description

and its 3' end overlaps with that of the latter

This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions| and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues| indicating that this protein is a major ISG15-specific protease

This gene is implicated in B cell development and lymphomagenesis

The retinoblastoma (Rb) tumor suppressor family includes the retinoblastoma protein Rb (p105)

which suggested its role in RAD51 related DNA recombination and repair

FXYD3 Rabbit Polyclonal Antibody, 50ul Deep Well Plates and its 3' end overlapsThis gene belongs to a small family of FXYD domain containing regulators of Na+ K+ ATPases which share a 35 amino acid signature sequence domain beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion pumps and ion channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript

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