AXIN1 Polyclonal Antibody, 50ul Metabolic enzymes Isoform 2 and isoform 3

Isoform 2 and isoform 3 are poorly detected in heart

|tissue specificity:Expressed in ovarian and colorectal cancer cell lines (at protein level)

Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2)

and may play a role in cell interactions with the extracellular matrix

The encoded protein may play an antioxidant protective role in cells| and may contribute to the antiviral activity of CD8(+) T-cells

AXIN1 Polyclonal Antibody, 50ul Metabolic enzymes Isoform 2 and isoform 3This gene encodes a cytoplasmic protein which contains a regulation of G protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta 1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The