Glypican-3 Polyclonal Antibody, 50ul Cell Proliferation This gene encodes a member

This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) protein family| with an N-terminal PDZ domain| a central src homology 3 region (SH3)| and a C-terminal guanylate kinase-like (GUK) domain

and may act as a DNA unwinding enzyme

PTM:Ser-376 and Thr-581 phosphorylation is required for kinase activity

This gene product interacts with Parkin and is involved in juvenile Parkinson disease

The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen

Glypican-3 Polyclonal Antibody, 50ul Cell Proliferation This gene encodes a memberCell surface heparan sulfate proteoglycans are composed of a membrane associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. Glypican 3 encoded by GPC3 can