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4E-BP1(Phospho Ser65) Polyclonal Antibody, 50ul Plasma Mutations in this gene have

SKU: 58716327886

4.2
SEK162.00 SEK198.00

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4E-BP1(Phospho Ser65) Polyclonal Antibody, 50ul Plasma Mutations in this gene haveThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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Description

Mutations in this gene have been associated with autosomal recessive megalencephaly

and are postulated to function as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells

Mixed lineage kinase domain-like protein contains a protein kinase-like domain

The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain

It is very similar to the family member HNRPH1

4E-BP1(Phospho Ser65) Polyclonal Antibody, 50ul Plasma Mutations in this gene haveThis gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E) which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV

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