Hairless Polyclonal Antibody, 50ul Gloves Multiple transcript variants encoding different

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

The eukaryotic translation initiation factor 4E binding protein 1 directly interacts with eukaryotic translation initiation factor 4E (eIF4E)

and is induced by transforming growth factor-beta (TGF-beta) to repress TGF-beta receptor II gene expression

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family

Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P)

Hairless Polyclonal Antibody, 50ul Gloves Multiple transcript variants encoding differentHR encodes a protein that is involved in hair growth. Protein hairless functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of Protein hairless is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this